Juvenile Onset Systemic Sclerosis
نویسندگان
چکیده
منابع مشابه
Juvenile-onset systemic sclerosis: children are not small adults.
The majority of childhood-onset rheumatic diseases differ markedly in presentation and management from their equivalent adult conditions, and juvenile-onset systemic sclerosis (JSSc) is no exception. Chronic ill health from any cause in childhood impacts heavily, not only on physical growth and development, but also in terms of social, educational and psychological development. Even localized s...
متن کامل[Juvenile Systemic Sclerosis].
mento cutâneo, evoluindo para áreas de despigmentação cutânea em ‘sal e pimenta’ (Fig. 1), e aparecimento de úlceras digitais (Fig. 2). Actualmente medicada com metotrexato subcutâneo, metilprednisolona e bosentan. A ESJ tem uma incidência de 0,27 casos por milhão de crianças1 e apresenta particularidades que a distinguem das formas adultas de esclerose sistémica.2 A abordagem terapêutica em id...
متن کاملLeflunomide in systemic onset Juvenile idiopathic arthritis.
Methotrexate, the mainstay of treatment in Juvenile idiopathic arthritis, might not be effective in a few patients of polyarticular and systemic onset juvenile idiopathic arthritis. Use of biologicals like TNF-a blockers, the next line of preferred drugs is constrained by the high cost. We successfully used leflunomide in four patients.
متن کاملThalidomide for systemic onset juvenile idiopathic arthritis.
Systemic onset juvenile idiopathic arthritis (SOJIA) is the most common autoimmune auto inflammatory disease in childhood. A sizeable number of these patients run a recalcitrant disease course, resistant to the conventional line of management, ultimately resulting in permanent disability from joint destruction, local growth deformities or iatrogenic side effects. The new biological agents altho...
متن کاملJuvenile systemic sclerosis: review of 15 patients
Results Results: Fifteen patients were identified and included in the analysis, 3 of them were overlap syndromes. Eleven girls (73%), 13 (87%) Caucasians, with a mean age at diagnosis of 11.1±3.0 (3–15) years and a mean disease duration of 7.2±4.2 years (8 months-17 years). In 14 (93%) cases, the first symptom attributable to JSSc was Raynaud’s phenomenon, followed by arthritis and/or puffy han...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1984
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107688407700916